Idiopathic Lymphoid Hyperplasia: a role for commensal microbiota?

Joana Vilela da Silva, Bruno Domingues, Rita Gama, Sandra Gerós, Eugénia Castro, Artur Condé

Resumen

Lymphoid hyperplasia is a reactive lesion of lymphoid tissue, considered the extranodal equivalent of a reactive lymph node.

Although its etiology remains elusive, mucosal colonization with specific strains of bacteria was previously proposed in the literature as a possible etiologic agent.

In this paper, we report two clinical cases of reactive lymphoid hyperplasia, indistinguishable from malignancy, and we discuss the interaction between the microbiome and the epithelial lining that may contribute to the etiology of this condition.

Palabras clave

lymphoid hyperplasia; actinomyces; microbiome; tonsillar hypertrophy.

Texto completo:

PDF HTML

Referencias

Gromet M, Homer MJ, Carter BL. Lymphoid hyperplasia at the base of the tongue. Spectrum of a benign entity. Radiology. Sep 1982;144(4):825-828.

Hope N, Patricia Smith C, Moran M, Primrose W. An unusual case of lingual tonsillar hypertrophy. Clinical case reports. May 2016;4(5):526-527.

Hwang MS, Salapatas AM, Yalamanchali S, Joseph NJ, Friedman M. Factors associated with hypertrophy of the lingual tonsils. Otolaryngol Head Neck Surg. May 2015;152(5):851-855.

Brodsky L, Moore L, Stanievich JF, Ogra PL. The immunology of tonsils in children: the effect of bacterial load on the presence of B- and T-cell subsets. Laryngoscope. Jan 1988;98(1):93-98.

Cervantes-Barragan LA-Ohoo, Chai JNA-Ohoo, Tianero MDA-OhooX, et al. Lactobacillus reuteri induces gut intraepithelial CD4+CD8alphaalpha+ T cells. 20170804 (1095-9203 (Electronic)).

Kutluhan A, Salviz M, Yalciner G, Kandemir O, Yesil C. The role of the actinomyces in obstructive tonsillar hypertrophy and recurrent tonsillitis in pediatric population. Int J Pediatr Otorhinolaryngol. Mar 2011;75(3):391-394.

van Lierop AC, Prescott CA, Sinclair-Smith CC. An investigation of the significance of Actinomycosis in tonsil disease. Int J Pediatr Otorhinolaryngol. Dec 2007;71(12):1883-1888.

Rankow RM, Abraham DM. Actinomycosis: masquerader in the head and neck. The Annals of otology, rhinology, and laryngology. Mar-Apr 1978;87(2 Pt 1):230-237.

Pezier TF, Kastrinidis N, Widmer GM, Huber GF, Probst R. Fatally invasive actinomycosis masquerading as a tonsillar carcinoma. Head & neck. Dec 2014;36(12):E129-130.

Floch P, Megraud F, Lehours P. Helicobacter pylori Strains and Gastric MALT Lymphoma. LID - E132 [pii] LID - 10.3390/toxins9040132 [doi]. 20170411 (2072-6651 (Electronic)).

Kinnari TJ. The role of biofilm in chronic laryngitis and in head and neck cancer. Current opinion in otolaryngology & head and neck surgery. Dec 2015;23(6):448-453.

Enlaces refback

  • No hay ningún enlace refback.


Bookmark and Share